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أدويه _ الجهاز العصبي المركزي 1

#Pharmacology_of_CNS 

#CNS


#Drugs_for_Neurodegenerative_Diseases


الليلة حا نتكلم عن ال

 NEUROTRANSMISSION IN THE CNS


❄️في تشابه في ال neurons بالنسبة للCNS والANS في انهم الاتنين بستخدمو ال neurotransmitter عشان يحصل ليها

recognition by the membrane receptor 

بس برضو في اختلافات بينهم ممكن نلخصها في 👇

⭐️The circuitry of the CNS is much more complex than that of the ANS

⭐️number of synapses in the CNS  

is far greater

⭐️The CNS contains powerful  

networks of inhibitory neurons 

⭐️CNS communicates through the use of multiple neurotransmitters, whereas the ANS uses only two primary neurotransmitters, acetylcholine and norepinephrine.


حا نتكلم شوية عن ال SYNAPTIC POTENTIALS

💠In the CNS, receptors at most synapses are coupled to ion channels.

ارتباط ال neurotransmitter بال receptors بيؤدي في النهاية ل 

change in the ionic composition across the membrane producing either depolarization or hyperpolarization of the postsynaptic membrane, depending on the specific ions and the direction of their movement.


🌀Neurotransmitters can be classified as either excitatory or inhibitory,depending on the nature of the action they elicit.


✅Excitatory pathways

Stimulation of excitatory neurons causes a movement of ions that results in a depolarization of the postsynaptic membrane.

قد يعجبك ايضا

✅Inhibitory pathways

Stimulation of inhibitory neurons causes movement of ions that  

results in a hyperpolarization of the postsynaptic membrane


🔘حا نختم البوست بمقدمة بسيطة كدا عن ال Neurodegenerative diseases


🔹Neurodegenerative diseases of the CNS include Parkinson’s disease,Alzheimer’s disease,Multiple sclerosis (MS), and Amyotrophic Lateral Sclerosis (ALS) . These devastating illnesses are characterized by the progressive loss of selected neurons in discrete brain areas, resulting in characteristic disorders of movement, cognition, or both.


حا نقيف هنا وحا نتكلم البوست الجاي عن ال

PARKINSON’S DISEASE




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